Connectivity of brain stem circuits

Principal Investigator: David Kleinfeld
UCSD Neuroscience
Title: "Revealing the connectivity and functionality of brain stem circuits"
BRAIN Category: Understanding Neural Circuits (RFA NS-14-009)

Dr. Kleinfeld and his colleagues will use a variety of tools and techniques to create detailed maps of circuits in the brainstem, the region that regulates many life-sustaining functions such as breathing and swallowing, and match the circuits to actions they control.

Optogenetic mapping of synaptic activity

Principal Investigator: John Yu-Luen Lin
Neuroscience at UCSD
Title: "Optogenetic mapping of synaptic activity and control of intracellular signaling"
BRAIN Category: Large-Scale Recording-Modulation - New Technologies (RFA NS-14-007)

Dr. Lin's team will create molecules that, when they are triggered by a pulse of light, allow scientists to test for communication between neurons in specific circuits of the brain.

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